PO-05-159 IMPACT OF ARRHYTHMIAS IN PATIENTS ADMITTED WITH SARCOIDOSIS: A NATIONWIDE PERSPECTIVE

Sarcoidosis is a chronic granulomatous disorder with multiorgan involvement. Cardiac sarcoidosis characterized by the growth of granulomas in any part heart which portends poor prognosis. These can cause conduction abnormalities. However, less known about in-hospital outcomes patients who have concurrent arrhythmias. We aimed to identify whether arrhythmia impacted these outcomes. Objective was study impact arrhtymias on sarcoidosis. queried National Inpatient Sample (NIS) database 2018- 2020. Adults admitted primary or secondary diagnosis were included. This population stratified into those and without {atrial fibrillation [AF], atrial flutters, SVTs, blocks [first, second degree, complete (CHB)], ventricular tachycardia [VT] [VF]}. Demographics association other comorbidities studied. Multivariate regression analysis performed arrhythmias taking mortality as outcome total hospital cost secondary. A 383385 hospitalised had Of those, 85205 (22.22%) Mean age 59 years 54.03% females. Traditional cardiac risk factors like diabetes mellitus (39.79% vs 37.61%, p<0.05),and hyperlipidemia (48.39% 38.79%, p<0.01) more prevalent cohort sarcoid The prevalence valvular abnormalities(25.12% 16.85%,p<0.01), CAD (33.32% 17.72%, old myocardial infarction (8.9% 5.32%, also significantly higher patients. After adjusting for covariates, odds VF, VT, CHB AF adult (table 1). charge considerably concomitant concludes that how presence underlying leads worse terms cost. findings necessitate need further research understand pathophysiology cohort. will help guiding therapeutic interventions prevent burden improve patient