PO-01-226 RACIAL DIFFERENCES AND SIMILARITIES IN ATRIAL FIBRILLATION EPIDEMIOLOGY, RISK FACTORS, AND MORTALITY IN COMMUNITY-BASED COHORTS: RESULTS FROM THE KOREAN NHIS-HEALS AND UK BIOBANK STUDIES
نویسندگان
چکیده
Atrial fibrillation (AF) is associated with mortality, morbidity, and medical costs. Despite the increasing public health importance of AF, race-specific disease distributions associations between clinical risk factors AF have received limited attention. This study aimed to compare established in white Europeans from UK Biobank Asian subjects Korean NHIS-HEALS (National Health Insurance Service-Health Screening) study. included 402,229 484,406 patients without a diagnosis nonvalvular cohort Biobank, respectively. The incidence its common factors, biomarkers, prevalent cardiovascular disease, their attributable by race were examined. median follow-up time was 11.8 years (interquartile range [IQR] 11.1–12.6) 7.6 (IQR 7.0–8.2) NHIS-HEALS. Fewer cases observed (N=9182; 2.3%) than (N=25312; 5.2%). Cardiovascular comorbidities, glucose levels an increased new-onset both cohorts, significant interactions country for body mass index (BMI), economic status, smoking history, history heart failure, cholesterol level. BMI more strongly related [hazard ratio (HR), 1.31; 95% confidence interval (CI), 1.29–1.33] compared (HR, 1.11; CI, 1.09–1.14), relative 1.18 (95% 1.15–1.21). Total inversely incident cohorts 0.86; 0.85–0.87 versus 0.91; 0.89–0.93 NHIS-HEALS), 0.95 0.92–0.97). Attributable proportion most classical similar studies. In this first large-scale comparison Caucasian populations, cumulative developing higher Korea over lifespan. Higher BMI, smoking, lower total Asians.
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2023
ISSN: ['1556-3871', '1547-5271']
DOI: https://doi.org/10.1016/j.hrthm.2023.03.589