Pneumocystis jirovecii pneumonia following everolimus treatment of metastatic breast cancer
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Pneumocystis jirovecii pneumonia following everolimus treatment of metastatic breast cancer
Everolimus is an inhibitor of mammalian target of rapamycin with anti-tumour activity. While everolimus is known to cause drug-induced pneumonitis, it is rarely associated with Pneumocystis jirovecii pneumonia (PJP). We report a patient on everolimus therapy for metastatic breast cancer that developed PJP. Diagnosis was based on clinical features and a quantitative polymerase chain reaction for...
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Jose M. Varela1, Francisco J. Medrano1, Eduardo Dei-Cas2,3 and Enrique J. Calderón1 1Instituto de Biomedicina de Sevilla and CIBER de Epidemiología y Salud Pública, Internal Medicine Service, Virgen del Rocío University Hospital. Seville, 2Parasitology-Mycology Service (EA4547), Centre of Biology Pathology, Lille-2 University Hospital Centre, Faculty of Medicine, Univ. Lille Nord de France, 3Bi...
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Pneumocystis pneumonia (PcP) is a serious fungal infection among immunocompromised patients. In developed countries, the epidemiology and clinical spectrum of PcP have been clearly defined and well documented. However, in most developing countries, relatively little is known about the prevalence of pneumocystosis. Several articles covering African, Asian and American countries were reviewed in ...
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ژورنال
عنوان ژورنال: Medical Mycology Case Reports
سال: 2014
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2014.08.007