Platelets attenuate monocrotaline-induced liver injury
نویسندگان
چکیده
منابع مشابه
Basement membrane and matrix metalloproteinases in monocrotaline-induced liver injury.
Monocrotaline (MCT) is a pyrrolizidine alkaloid that causes liver injury in animals. In rats, injury is characterized by sinusoidal endothelial cell (SEC) damage and centrilobular parenchymal cell necrosis. Loss of endothelium is a possible outcome of the action of matrix metalloproteinases (MMPs), specifically MMP-9 from neutrophils and SECs and MMP-2 from SECs, on basement membrane collagen. ...
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ژورنال
عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society
سال: 2021
ISSN: 2435-4953
DOI: 10.1254/jpssuppl.94.0_3-p2-33