Platelet shape in idiopathic thrombocytopenic purpura and platelet shape changing factor (PSCF) in plasma.
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چکیده
منابع مشابه
Platelet aggregation in chronic idiopathic thrombocytopenic purpura.
A method for washing platelets by albumin density gradient separation has been modified to prepare platelet rich plasma of thrombocytopenic patients for platelet aggregation studies. The concentration procedure, consisting of centrifuging platelets into a specific gravity gradient between plasma and 40-45% aqueous solution of bovine albumin, does not affect platelet aggregation adversely. Plate...
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Chronic idiopathic thrombocytopenic purpura (chronic ITP) is an autoimmune disorder characterized by bleeding tendency and the presence of auto-antibody to platelets. Quantitative analysis of the level of anti-platelet antibodies and platelet associated antibodies is now possible. Furthermore, recent immunological techniques have enabled us to detect target platelet antigens in chronic ITP. In ...
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Platelet survival has been measured in 16 patients with idiopathic thrombocytopenic purpura. Of this group, three patients had a normal result and surface counting did not show high splenic uptake. The clinical features of these patients are described. These patients have remained well for several years without treatment.
متن کاملPlatelet functional defects in thrombocytopenic purpura.
With the technical assistance of \Iiss MAuIIEEN JENNER T HERE IS now considerable evidence to suggest that the hemorrhagic manifestations of thrombocytopenic purpura and certain other disorders are probably due largely to deranged platelet function rather than to a reduction in platelet numbers. It is, of course, true that associated vascular changes also play an important role in thrombocytope...
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A method for the measurement of immunoglobulin G associated with gel-filtered platelets is described and finding in 70 control subjects and 37 patients with immune thrombocytopenic purpura (ITP) are reported. Control platelet-associated IgG (PAIgG) levels (nanograms IgG per 10(9) platelets) averaged (+/-SD) 1231+/-424; samples studied after 24 and 48 hr remained within the control range. PAIgG ...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1984
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.15.420