Platelet miRNA Expression in Patients with Sticky Platelet Syndrome

Abstract Sticky platelet syndrome (SPS) is a disorder with familial occurrence and autosomal dominant trait characterized by hyperaggregability in response to low concentration of adenosine diphosphate (ADP) and/or epinephrine (EPI). The etiology SPS may be associated microRNAs (miRNAs), which are considered as potential biomarkers function antiplatelet therapy. We were monitoring the expression miRNAs patients laboratory diagnosed healthy controls. have found statistically significant increased both miR-423-5p miR-338-3p well decreased miR-425-5p between group type II controls, seems an interesting issue for further research.