Platelet Function in Viral Immunity and SARS-CoV-2 Infection

Abstract Platelets, as nonnucleated blood components, are classically recognized for their pivotal role in hemostasis. In recent years, however, accumulating evidence points to a nonhemostatic platelets, active participants the inflammatory and immune responses microbial organisms infectious diseases. This stems from ability of activated platelets secrete plethora immunomodulatory cytokines chemokines, well directly interplaying with viral receptors. While much attention has been given cytokine storm severity coronavirus disease 2019 (COVID-19), less is known about contribution severe acute respiratory syndrome 2 (SARS-CoV-2) infection. Here, we give brief overview on platelet antiviral immunity response during SARS-CoV-2