Platelet factor 3 availability

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Effects of Cerebral Malaria on Platelet count, Platelet factor – 3 and Platelet aggregate availability in children

Malaria is a formidable global parasitic infection that presents a major health challenge in tropical countries especially among children. A total of 130 children (65 males and 65 females) with cerebral malaria and the same number and ratio for healthy children were considered as control; all aged 1-9 years. Standard haematological method was used to determine the Packed cell volume, platelet a...

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Flow Cytometric Measurement of CD41/CD61, CD42b Platelet Receptors and Platelet Factor 3 Activity in Lyophilized Infusible Platelet Membrane Preparation

Background: The short life time of human platelet units has led to a chronic shortage of fresh platelets in blood transfusion centers. Many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. Infusible platelet membrane (IPM) prepared from fresh or outdated human platelets have been developed as an altern...

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Haemarthroses after total knee arthroplasty caused by an isolated platelet factor 3 availability defect.

We present seven patients with recurrent haemarthroses after total knee arthroplasty, caused by an inherent platelet function defect. These patients developed painful knee swelling, persistent bleeding and/or wound breakdown, a platelet factor 3 availability defect being identified in all cases. Surgical exploration, with joint debridement, lavage and synovectomy, was performed in four patients...

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Platelet Factor 3 Based-clotting Time Assay as a Quality Marker for Long-term Storage of Platelet Concentrates

Background: Platelets rapidly lose their qualities usually after 5 day of storage. Different standard methods have been recommended to check the quality of platelets during storage which some of them show better correlation with other quality markers during storage. The purpose of this study was to demonstrate if platelet factor 3 (PF3) assay could be an indicator of storage lesion and provide ...

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Flow Cytometric Measurement of CD41/CD61 and CD42b Platelet Receptors and Clotting Assay of Platelet Factor 3 During Long Term-Storage of Platelet Concentrates

Background: The purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (PCs) on major platelet receptors CD42b and CD41/CD61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (PF3) assay. Materials and Methods: Six random units of conventional platelet conce...

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ژورنال

عنوان ژورنال: Blood & Vessel

سال: 1976

ISSN: 0386-9717,1884-2372

DOI: 10.2491/jjsth1970.7.533