Platelet and fibrinogen kinetics in the chronic myeloproliferative disorders

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Increased platelet-fibrinogen affinity in patients with myeloproliferative disorders.

Patients with myeloproliferative disorders (MPD) are known to have some abnormalities of platelet glycoproteins (Gp). Quantitative changes of the Gp Ib, IIb-IIIa, and/or their glucidic content have been reported. Since the Gp IIb-IIIa complex plays a major role in fibrinogen binding by activated platelets, we measured the platelet fibrinogen affinity in nine patients with polycythemia vera (PV)...

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ژورنال

عنوان ژورنال: Cancer

سال: 1972

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(197212)30:6<1444::aid-cncr2820300605>3.0.co;2-l