Platelet Activation in Stored Platelet Concentrates: Comparision of Two Methods Preparation
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چکیده
منابع مشابه
Platelet Activation in Stored Platelet Concentrates: Comparision of Two Methods Preparation
Preparation conditions and storage of platelet for transfusion may cause platelet activation, which contributes to decreased ability of stored platelet to function and to survive in vivo after transfusion compared with that seen with freshly prepared platelets [1-4]. Platelet transfusion therapy has played an important role in the management of patients [2,4]. Today, platelet concentrates are r...
متن کاملInfluence of Different Methods Preparation on Platelet Activation in Stored Platelet Concentrates
Platelet transfusion therapy has played an important role in the management of patients [4]. Today, a variety of methods for the preparation of platelets for transfusion are available ,which may be due to different processing systems such as apheresis ,buffy coat and platelet rich plasma platelet concentres methods [5,6]. Processing and storage may affect both platelet quality and function and ...
متن کاملEvaluation of Biochemical Parameters of Platelet Concentrates Stored in Plasma or in A Platelet Additive Solution (Composol)
Abstract Objective Removing plasma from the platelet concentrate (PC) medium could be an effective way to increase the safety of this product. The goal of this study was to compare PC stored in plasma or in an additive solution (Composol) with in vitro testing. Materials and Methods Fifty-four single donor PCs were prepared from Iranian Blood Transfusion Organization (IBTO). Each PC unit wa...
متن کاملAn Overview on Platelet-derived Microparticles in Platelet Concentrates: blood collection, method preparation and storage
Preparations of platelet concentrates (PCs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (PMPs) with high coagulant activity that may change platelet efficacy and safety issues. High shear stress could cause shedding of PMPs from the platelet plasma membrane, platelet aggregation, and activation of the co...
متن کاملComparative Study of Four Platelet-Rich Plasma Methods for Preparing Platelet Concentrates
Background: Platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. Platelet concentrates can be prepared by the apheresis method or from the whole blood using the Buffy-coat or Platelet-rich plasma methods. The purpose of this study was to compare four variations of platelet-rich plasma method based on double...
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ژورنال
عنوان ژورنال: Journal of Blood Disorders & Transfusion
سال: 2011
ISSN: 2155-9864
DOI: 10.4172/2155-9864.1000107