Plasmodium vivax trophozoite-stage proteomes
نویسندگان
چکیده
منابع مشابه
A large scale Plasmodium vivax- Saimiri boliviensis trophozoite-schizont transition proteome
Plasmodium vivax is a complex protozoan parasite with over 6,500 genes and stage-specific differential expression. Much of the unique biology of this pathogen remains unknown, including how it modifies and restructures the host reticulocyte. Using a recently published P. vivax reference genome, we report the proteome from two biological replicates of infected Saimiri boliviensis host reticulocy...
متن کاملDetermining the Plasmodium vivax VCG-1 strain blood stage proteome.
Plasmodium vivax is the second most prevalent parasite species causing malaria in humans living in tropical and subtropical areas throughout the world. There have been few P. vivax proteomic studies to date and they have focused on using clinical isolates, given the technical difficulties concerning how to maintain an in vitro culture of this species. This study was thus focused on identifying ...
متن کاملExperimentally induced blood-stage Plasmodium vivax infection in healthy volunteers.
BACKGROUND Major impediments to development of vaccines and drugs for Plasmodium vivax malaria are the inability to culture this species and the extreme difficulty in undertaking clinical research by experimental infection. METHODS A parasite bank was collected from a 49-year-old woman with P. vivax infection, characterized, and used in an experimental infection study. RESULTS The donor mad...
متن کاملProteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites
Plasmodium falciparum and Plasmodium vivax cause the majority of human malaria cases. Research efforts predominantly focus on P. falciparum because of the clinical severity of infection and associated mortality rates. However, P. vivax malaria affects more people in a wider global range. Furthermore, unlike P. falciparum, P. vivax can persist in the liver as dormant hypnozoites that can be acti...
متن کاملPlasmodium Vivax Infection Impersonating Plasmodium Falciparum Malaria Plasmodium Falciparum Sıtmayı Taklit Eden Plasmodium Vivax Enfeksiyonu
A 73-year-old woman came to the casualty ward with symptoms of syncopal attacks, weakness, fever with chills and rigors. A provisional diagnosis of Plasmodium vivax malaria was made after the blood investigations. She had deranged renal function tests, altered sensorium and low platelet count. Repeated tests for P. falciparum (Card test) were negative. Glucose-6-Phosphate dehydrogenise (G6PD) l...
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ژورنال
عنوان ژورنال: Journal of Proteomics
سال: 2015
ISSN: 1874-3919
DOI: 10.1016/j.jprot.2014.12.010