Plasmin Triggers Cytokine Induction in Human Monocyte-Derived Macrophages
نویسندگان
چکیده
منابع مشابه
Plasmin triggers cytokine induction in human monocyte-derived macrophages.
OBJECTIVE Fibrinolytic activity is upregulated in atherosclerotic lesions, yet little is known about the role of plasmin in macrophage function. We postulated a direct effect of plasmin on human monocyte-derived macrophages. METHODS AND RESULTS Plasmin activates macrophages via the annexin A2 heterotetramer composed of annexin A2 and S100A10 with subsequent stimulation of Janus kinase JAK1/TY...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2007
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.107.142901