Plasma renin activity and aldosterone concentration in the human newborn.

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Plasma renin activity and aldosterone concentration in the human newborn.

Twenty-one healthy newborn infants whose mothers had normal pregnancies and deliveries were studied. Plasma renin activity (PRA) and plasma aldosterone concentration (PAldo) were measured by semimicro methods in cord blood and on the 6th day of life. PRA and PAldo were increased in cord blood compared with values previously found in healthy infants between 1 month and 1 year of age. There was a...

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Association of antithrombin activity with plasma aldosterone concentration and plasma renin activity in pregnant women.

OBJECTIVE To test the hypothesis that the blood antithrombin (AT) activity is correlated with the plasma aldosterone concentration (PAC), the plasma renin activity (PRA), and/or the PAC-to-PRA ratio during the late stage of pregnancy. METHODS The AT activity, PAC, and PRA were determined within 7 days prior to delivery in 47 women, consisting of 30 normotensive and 6 hypertensive women with s...

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Circadian changes in plasma renin activity and plasma aldosterone concentration in one-kidney hypertensive rats.

Circadian changes in plasma renin activity (PRA) and plasma aldosterone concentration (PAC) in normal and hypertensive rats were determined by measurements at 8 a.m., 4 p.m. and 12 midnight (MN). For the normals, PRA and PAC were highest at 4 p.m. Animals made hypertensive by constriction one renal artery with the other kidney intact were studied after 4, 5, 7 and 10 weeks; the clear-cut circad...

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Plasma aldosterone concentration at delivery and during the newborn period.

Aldosterone concentrations in plasma of women on normal sodium intake undergoing cesarean section were 3.7+/-1.4 ng/100 ml (mean+/-1 SD). These values were significantly lower (P < 0.001) than those observed in mothers on normal sodium diet, delivered by the vaginal route (14.9+/-7.0 ng/100 ml). A significant elevation (P < 0.001) of the concentrations was found if the mothers had been on sodiu...

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Aldosterone, plasma Renin activity, and aldosterone/renin ratio in a normotensive healthy pediatric population.

Primary aldosteronism is an important cause of secondary hypertension and is suspected in adults with an aldosterone/renin ratio > or =25. The normal aldosterone/renin ratio is unknown in children. The aim was to establish serum aldosterone, plasma renin activity, and aldosterone/renin ratio values in a healthy pediatric population. A cross-sectional study was performed in 211 healthy normotens...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1976

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.51.7.537