Plasma Hypoxanthine in Exteriorized, Acutely Asphyxiated Fetal Lambs
نویسندگان
چکیده
منابع مشابه
Fetal Lambs
Morphologic analyses of lungs from infants who died of severe aortic stenosis shortly after birth have shown increased pulmonary vascular smooth muscle and an increased number of pulmonary resistance vessels. These findings have been thought to be caused by in utero pulmonary venous, pulmonary arterial or right ventricular hypertension. To study this problem in the fetus, we created aortic sten...
متن کاملExperimental aortic stenosis in fetal lambs.
Morphologic analyses of lungs from infants who died of severe aortic stenosis shortly after birth have shown increased pulmonary vascular smooth muscle and an increased number of pulmonary resistance vessels. These findings have been thought to be caused by in utero pulmonary venous, pulmonary arterial or right ventricular hypertension. To study this problem in the fetus, we created aortic sten...
متن کاملPulmonary hemodynamics and vascular reactivity in asphyxiated term lambs resuscitated with 21 and 100% oxygen.
An increase in oxygen tension is an important factor in decreasing pulmonary vascular resistance (PVR) at birth. Birth asphyxia results in acidosis and increased PVR. We determined the effect of resuscitation with 21 vs. 100% O(2) on pulmonary hemodynamics, pulmonary arterial (PA) reactivity, and oxidant stress in a lamb model of in utero asphyxia. Term fetal lambs were acutely asphyxiated by i...
متن کاملMaternal plasma hypoxanthine levels in nonpreeclamptic twin pregnancies.
We have observed that the elevated plasma adenosine levels are associated with hyperuricemia in nonpreeclamptic twin pregnancies. In animal models, extracellular adenosine is taken up by cells to form adenine nucleotides or is degraded to other purine metabolites such as hypoxanthine, which is further metabolized to xanthine and uric acid. In this study, we measured plasma hypoxanthine levels t...
متن کاملDecline in lung liquid volume before labor in fetal lambs.
The volume of liquid in the fetal lung depends on the amount of liquid secreted across the pulmonary epithelium and the amount flowing through the trachea. Lung liquid volume (V1) and secretion rate Vs) were determined using an indicator-dilution technique, while tracheal flow rate (Vtr) was measured simultaneously with a bubble flowmeter. Least-squares regression analysis showed that in 10 chr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 1980
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198008000-00002