Plasma growth hormone concentration in corticosteroid-treated children

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Plasma growth hormone concentration in corticosteroid-treated children.

Endogenous plasma growth hormone concentrations were measured in 23 children who were receiving daily corticosteroid therapy and in 10 control asthmatic children who had not received steroids for at least 8 months. The growth hormone concentrations were similar in the two groups of patients both during the fasting state and after insulin-induced hypoglycemia. 12 children, who were studied while...

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Metabolic effects of human growth hormone in corticosteroid-treated children.

The effects of administered human growth hormone (HGH) were evaluated in dwarfed, prepubertal children who were receiving long-term corticosteroid therapy for a chronic disease. During 11 complete metabolic balance studies, the eight corticosteroid-treated children demonstrated impaired response to large doses of HGH with minimal nitrogen and no phosphorus retention. In contrast, two hypopituit...

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Fasting growth hormone in treated diabetic children.

REFERENCES Benzing, G., III, Schubert, W., Hug, G., and Kaplan, S. (1969). Simultaneous hypoglycemia and acute congestive heart failure. Circulation, 40, 209. Burnard, E. D., and James, L. S. (1961a). The cardiac silhouette in newborn infants: a cinematographic study of the normal range. Pediatrics, 27, 713. -, and(1961b). Failure of the heart after undue asphyxia at birth. Pediatrics, 28, 545....

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Melanocytic nevi in children treated with growth hormone.

There is concern that growth hormone (GH) therapy may influence the growth of melanocytic nevi. In a review of the experience of the National Cooperative Growth Study, we found no excess of skin cancer in children who were treated with GH. We also reviewed our experience in 90 children with GH deficiency and 24 with Turner syndrome. We found no difference in the nevi count between control subje...

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Growth hormone treatment in children with rheumatic disease, corticosteroid induced growth retardation, and osteopenia.

BACKGROUND In children with severe rheumatic disease (RD), treatment with corticosteroids (CS) is frequently needed and growth retardation and osteopenia may develop. A beneficial effect of human growth hormone (hGH) has been reported but mostly in trials without a control group. AIMS To study the effect of hGH on growth, bone mineral density (BMD), and body composition, taking the disease ac...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1968

ISSN: 0021-9738

DOI: 10.1172/jci105739