Plasma fibrinogen: now also an antidepressant response marker?

Fibrinogen and COPD: Now what?

Fibrinogen plasma concentration is an independent marker of haemodynamic impairment in chronic thromboembolic pulmonary hypertension

Fibrinogen has a crucial role in both inflammation and coagulation, two processes pivotal for the pathogenesis of pulmonary hypertension. We therefore aimed to investigate whether fibrinogen plasma concentrations a) are elevated in pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) and b) may serve as a novel biomarker for haemodynamic impairment. In...

Preoperative peripheral plasma fibrinogen level is an independent prognostic marker in penile cancer

BACKGROUND AND AIM High levels of peripheral plasma fibrinogen have recently been revealed that related to poor clinical prognosis in various types of malignant tumors. The purpose of this research was to identify the prognostic significance of the preoperative peripheral serum fibrinogen level in patients with penile cell carcinoma. METHODS This retrospective research included 72 penile canc...

Plasma fibrinogen is an accurate marker of disease activity in patients with polymyalgia rheumatica.

OBJECTIVE The overall aim of this study was to establish whether plasma fibrinogen was a superior biomarker of disease activity in active PMR than the standard biomarkers, ESR and CRP. METHODS Sixty patients with PMR were divided into active (n = 25) or inactive (n = 35) disease groups based on symptoms, physician assessment and biomarkers ESR and CRP. Plasma fibrinogen was assayed. Groups un...

Elevated plasma fibrinogen, psychological distress, antidepressant use, and hospitalization with depression: two large population-based studies.

OBJECTIVES Low-grade systemic inflammation may contribute to the development of depression. We tested the hypothesis that elevated plasma levels of the inflammatory marker fibrinogen are associated with psychological distress, use of antidepressant medication, and with hospitalization with depression in the general population. METHODS We examined 73,367 20-100 year old men and women from two ...