Plant Protease Inhibitors in Therapeutics-Focus on Cancer Therapy
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چکیده
منابع مشابه
Plant Protease Inhibitors in Therapeutics-Focus on Cancer Therapy
Plants are known to have many secondary metabolites and phytochemical compounds which are highly explored at biochemical and molecular genetics level and exploited enormously in the human health care sector. However, there are other less explored small molecular weight proteins, which inhibit proteases/proteinases. Plants are good sources of protease inhibitors (PIs) which protect them against ...
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It has been recognized for many years that the nutritive value and protein digestibility of many plant proteins, particularly those derived from legumes, are very poor unless subjected to cooking or some other form of heat treatment (Liener & Kakade, 1969). This beneficial effect of heat has beem generally attributed, at least in part, to the destruction of a unique class of proteins which have...
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Background and Aim: Advent of COVID-19 attracted the attentions of researchers to develop drugs for its treatment. Besides efforts on developing new drugs, screening available drugs for efficacy on COVID-19 could be an urgent action of initiating its pharmacotherapy. In this study, efficacy of HIV protease inhibitors on COVID-19 protease has been examined. Methods: Molecular docking based scree...
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Proteases, though essentially indispensable to the maintenance and survival of their host organisms, can be potentially damaging when overexpressed or present in higher concentrations, and their activities need to be correctly regulated. An important means of regulation involves modulation of their activities through interaction with substances, mostly proteins, called protease inhibitors. Some...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2016
ISSN: 1663-9812
DOI: 10.3389/fphar.2016.00470