Planarian GSK3s are involved in neural regeneration
نویسندگان
چکیده
منابع مشابه
Fundamentals of planarian regeneration.
The principles underlying regeneration in planarians have been explored for over 100 years through surgical manipulations and cellular observations. Planarian regeneration involves the generation of new tissue at the wound site via cell proliferation (blastema formation), and the remodeling of pre-existing tissues to restore symmetry and proportion (morphallaxis). Because blastemas do not repla...
متن کاملA quantitative metabolomics peek into planarian regeneration.
The fresh water planarian species Schmidtea mediterranea is an emerging stem cell model because of its capability to regenerate a whole animal from a small piece of tissue. It is one of the best model systems to address the basic mechanisms essential for regeneration. Here, we are interested in studying the roles of various amines, thiols and nucleotides in planarian regeneration, stem cell fun...
متن کاملMuscle Cells Provide Instructions for Planarian Regeneration
Regeneration requires both potential and instructions for tissue replacement. In planarians, pluripotent stem cells have the potential to produce all new tissue. The identities of the cells that provide regeneration instructions are unknown. Here, we report that position control genes (PCGs) that control regeneration and tissue turnover are expressed in a subepidermal layer of nonneoblast cells...
متن کاملPlanarian Regeneration: Its End Is Its Beginning
In 1901, Thomas Hunt Morgan wrote: " The fact that the process of regener-ation is useful to the organism cannot be made to account for its existence in the organism " (Morgan, 1901). Although such words may strike us today as being counter to the general concepts of natural selection, Morgan reached this conclusion after an exhaustive study of regeneration in both plants and animals (Morgan, 1...
متن کاملRibonucleic acid metabolism during planarian regeneration.
A method for the extraction of total RNA of the planarian Polycelis tenuis is described. This technique has been applied to the study of RNA synthesis in the course of regeneration. Synthesis of RNA begins 7 hrs after sectioning and proceeds in two phases. The first phase, from 7 to 21 hr is characterized by an increased rate of (3H) orotic acid incorporation into RNA up to the 18th after secti...
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ژورنال
عنوان ژورنال: Development Genes and Evolution
سال: 2008
ISSN: 0949-944X,1432-041X
DOI: 10.1007/s00427-008-0206-3