Pituitary Peptides
نویسندگان
چکیده
منابع مشابه
Opioid peptides and pituitary function.
A number of in-vitro model systems have been introduced for the study of the action of morphine-like drugs. Their usefulness depends on their relative simplicity, compared to the brain and central nervous system, and on the good correlation observed between potencies in the models and potencies in the whole animal. For example, the contractions of the isolated guinea\x=req-\ pig ileum and mouse...
متن کاملPro-opiomelanocortin Peptides in Mouse Pituitary Cells*
Pro-opiomelanocortin (POMC) is glycosylated and proteolytically cleaved to produce a number of smaller peptide hormones including adrenocorticotropic hormone (ACTH) and endorphin in mammalian pituitary and the mouse pituitary cell Line AtT-20/DI6,. When glycosylation of POMC is inhibited in AtT-20 cells with the drug tunicamycin, a 26,000-dalton protein appears in place of the glycosylated 29,0...
متن کاملBronchodilation by pituitary adenylate cyclase-activating peptide and related peptides.
Pituitary adenylate cyclase-activating peptide (PACAP) is present in nerves in the vicinity of bronchial and vascular smooth muscle in the airways. At least one endogenous form of PACAP, PACAP 1-27, has high affinity binding sites in the lung, probably including cholinergic nerve terminals, bronchial smooth muscle, epithelial and mononuclear inflammatory cells. The mechanism of action for PACAP...
متن کاملThe Anterior Pituitary Gland - Co-Ordinating an Alphabet of Peptides
The pituitary has been described as the Master Gland, even as we progress through the contemporary era of comprehensive proteomic arrays [1, 2]. The label is a reflection of the range of the gland’s influences. The variety of contributions that the anterior pituitary gland makes to so many of the clearly observable events as well as covert metabolic processes in the body (e.g. stress, reproduct...
متن کاملPituitary peptides and the suppression of memory by puromycin.
It has previously been shown that the expression of memory of maze-learning in mice is blocked by intracerebrally-injected puromycin one or more days after the training experience, and that bilateral adrenalectomy before training protects memory against this effect of puromycin. Purified cortrophin gel, injected subcutaneously up to 3 days before training, has now been found to give results lik...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1971
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)77188-9