منابع مشابه
New optimising feature in SPICE
The field of optimisation is still not appropriately covered in modern computer programs for circuit analysis as SPICE, which was originally developed at the University of California at Berkeley. The last official release of SPICE was published in 1992 and includes interactive interpreter language called Nutmeg, which is at first glance very convenient for coding optimisation loops. But it turn...
متن کاملPotential role of a nutraceutical spice (Allium hirtifolium) in reduction of atherosclerotic plaques
Introduction: Spices are now considered as agents that not only can prevent but may even treat chronic diseases. This study was aimed to investigate the effects of Allium hirtifolium as a hypolipidemic and anti-atherosclerotic substance in hypercholesterolemic rabbits. Methods: Twenty four adult New Zealand male rabbits were divided randomly into 3 groups of 8 animals each and treated for 60 da...
متن کاملCurcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme Activities.
Inhibition of cytochrome P450 (P450) enzymes (CYP) has been shown to lower the metabolism of drugs that are P450 substrates and to consequently alter their pharmacokinetic profiles. Curcumin (CUR), piperine (PIP), and capsaicin (CAP) are spice components (SC) that inhibit the activities of a range of P450 enzymes, but the selection of which SC to be prioritized for further development as an adj...
متن کاملSpice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension
BACKGROUND Increase of blood pressure is accompanied by functional and morphological changes in the vascular wall. The presented study explored the effects of curcuma and black pepper compounds on increased blood pressure and remodeling of aorta in the rat model of experimental NO-deficient hypertension. METHODS Wistar rats were administered for 6 weeks clear water or L-NAME (40 mg/kg/day) di...
متن کاملPiperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells
Prostate cancer is the most common solid malignancy in men, with 32,000 deaths annually. Piperine, a major alkaloid constituent of black pepper, has previously been reported to have anti-cancer activity in variety of cancer cell lines. The effect of piperine against prostate cancer is not currently known. Therefore, in this study, we investigated the anti-tumor mechanisms of piperine on androge...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2019
ISSN: 1381-6128
DOI: 10.2174/1381612825666190701150803