Pineal indoleamine metabolism in pyridoxine-deficient rats
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چکیده
منابع مشابه
Thyroid function in pyridoxine-deficient young rats.
In pyridoxine-deficient young rats hypothalamic serotonin was decreased with no changes in the dopamine and noradrenaline content. Serum thyroxine and tri-iodothyronine concentrations were much lower in the deficient rats as compared to pyridoxine-supplemented controls. No significant difference between deficient and control groups in the serum TSH concentration was detected. Highly significant...
متن کاملHypothyroidism of hypothalamic origin in pyridoxine-deficient rats.
Pyridoxine-deficient young rats (3 weeks old) had significantly reduced levels of pituitary TSH, serum thyroxine (T4) and tri-iodothyronine (T3) compared with pyridoxine-supplemented rats. The status of the pituitary-thyroid axis of normal, pyridoxine-supplemented and pyridoxine-deficient rats was evaluated by studying the binding parameters of [3H](3-methyl-histidine2)TRH in the pituitary of t...
متن کاملImpairment of Antibody Response in Pyridoxine-deficient Rats
Striking impairment of the antibody response to sheep erythrocytes was found in pyridoxine-deficient rats. Deficiencies in the three other B factors required by the rat, and low protein feeding, having effects on body weight comparable to pyridoxine deficiency, failed to influence the antibody response studied. Confirming previous observations, a striking loss of thymic and lymphoid tissue occu...
متن کاملL-cystathionine in the urine of pyridoxine-deficient rats.
The work of Stefano & Diermeier (1956) on the effect of growth hormone upon the development of polyploidy in the liver is in keeping with the hypothesis that growth hormone is important in the growth ofthe liver. Proof ofthe hypothesis requires work on liver regeneration in hypophysectomized rats. Some preliminary experiments which we have performed gave no positive result, but investigations a...
متن کاملHyperglycemia in Pyridoxine Deficient Rats1
Xanthurenic acid, an abnormal metabolite of tryptophan (1, 2), which is pro duced in pyridoxine-deficient rats, is said to cause diabetes mellitus (3). In our laboratory Lin et al. (4) suggested that the deficiency of pyridoxine alone for a long time might cause, independently of the diabetogenic action of xanthurenic acid, abnormal carbohydrate metabolism leading to continuous hyperglycemia. T...
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ژورنال
عنوان ژورنال: Brain Research
سال: 1988
ISSN: 0006-8993
DOI: 10.1016/0006-8993(88)90312-5