Pimecrolimus Reduces Eosinophil Activation Associated with Calcium Mobilization
نویسندگان
چکیده
منابع مشابه
Pimecrolimus reduces eosinophil activation associated with calcium mobilization.
BACKGROUND Pimecrolimus is a calcineurin inhibitor that inhibits T cell and mast cell activation and effectively treats atopic dermatitis. However, its effects on eosinophils, a cell type implicated in allergic disease pathology, are unknown. Therefore, we examined the effects of pimecrolimus on eosinophil superoxide anion production, degranulation and survival. METHODS Purified eosinophils f...
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ژورنال
عنوان ژورنال: International Archives of Allergy and Immunology
سال: 2009
ISSN: 1018-2438,1423-0097
DOI: 10.1159/000189194