Pilocytic Astrocytoma with Specific Gene Signature
نویسندگان
چکیده
منابع مشابه
Pilocytic astrocytoma.
To cite: Lourenço EP, Nzwalo H, Sampaio MR, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015213013 DESCRIPTION Pilocytic astrocytoma (PA) is a benign tumour of childhood, often located in deep midline structures such as the brainstem and the cerebellum. Gross surgical resection is curative in the majority of patients. We report a case of recurrent PA di...
متن کاملPilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature.
Pilocytic astrocytomas are WHO grade I gliomas that occur predominantly in childhood. They share features of both astroglial and oligodendroglial lineages. These tumours affect preferentially the cerebellum (benign clinical course) and the optic pathway, especially the hypothalamo-chiasmatic region (poor prognosis). Understanding the molecular basis responsible for the aggressive behaviour of h...
متن کاملSpinal hemangioblastoma combined with pilocytic astrocytoma
The combination of vascular anomalies with gliomas is rarely seen in the CNS, and is defined as "angioglioma". However, the definition, category, and histopathogenesis of angiogliomas remain controversial. Here, we present an unusual case of spinal hemangioblastoma (HB) combined with pilocytic astrocytoma (PA). Spinal MRI revealed lesions extending from T9 to T12 segments, in a "sandwich-like" ...
متن کاملPrimary Pilocytic Astrocytoma with Malign Transformation
Pilocytic astrocytoma is a slow-growing brain tumor that occurs more often in children with a benign course and long clinical history compared to diffuse astrocytomas. Pilocytic astrocytomas may rarely show malignant transformation and radiotherapy plays a key role in the treatment of malignant transformation. In this study, we present a pilocytic astrocytoma case with no radiotherapy history a...
متن کاملUnusual Presentation of Pilocytic Astrocytoma
Pilocytic astrocytoma (PA) is the benign variant of astrocytic tumours. Pilocytic(Greek word Pilos=hair) refers to frequent presence of cells with bipolar hairlike processes. Pilocytic tumours are juvenile astrocytomas commonly presenting during first two decades of life with a lowered occurrence in adults. Cerebellum is the favoured site. Spinal cord is the rare site of presentation. We report...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2009
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-23-7-10