منابع مشابه
Peroxisome proliferation and hepatocarcinogenesis.
Peroxisome proliferators constitute a novel class of non-mutagenic hepatocarcinogens, all of which induce a similar pleiotropic response consisting of hepatomegaly, proliferation of peroxisomes in the liver parenchyma] cells and the induction of several hepatic enzymes, particularly those of the peroxisomal fatty acid /3oxidation system (1—3). Presently several structurally dissimilar hypolipid...
متن کاملPeroxisome division and proliferation in plants.
Peroxisomes are eukaryotic organelles with crucial functions in development. Plant peroxisomes participate in various metabolic processes, some of which are co-operated by peroxisomes and other organelles, such as mitochondria and chloroplasts. Defining the complete picture of how these essential organelles divide and proliferate will be instrumental in understanding how the dynamics of peroxis...
متن کاملPeroxisome proliferation and hepatotoxicity in rodents.
Gariot, P.. Barrat. E., Mejean, L., Pointel, J . P., Drouin, P. & Debry, G. (1983)Arch. Toxicol. 53, 151-163 Gibson, G. G . , Orton, T. C. & Tamburini, P. P. (1982) Biochem. J. 203,161-168 Gray, T. J . B., Beamand, J . A., Lake, B . G., Foster, J . R. & Gangolli, S. D. (1982) Toxicol. Lett. 10,273-279 Gray, T. J . B., Lake, B. G.. Beamand, J . A,, Foster, J . R. & Gangolli, S. D. (1983) Toxicol...
متن کاملPeroxisome proliferation in response to xenobiotics.
Mantle, T. J., Mannervik, B. and Hayes, J. D., eds.), pp. 2 1 1-22 1, CRC Press, Boca Raton, FL Andersson, C., Mosialou, E., Weinander, R., Hebert, H. and Morgenstern, R. (1993) in Structure and Function of Glutathione Transferases (Tew, K. D., Pickett, C. B.. Mantle, T. J., Mannervik, B. and Hayes, J. D., eds.), pp. 109-1 16, CRC Press, Boca Raton, FL Nicholson, D. W (1993) in Structure and Fu...
متن کاملSpecies differences in hepatic peroxisome proliferation.
A number of compounds including the hypolipidaemic drug clofibrate (ethyl 2[p-chlorophenoxyl isobutyrate) and the plasticizer di-(2-ethylhexyl)phthalate (DEHP) have been shown to produce liver enlargement and hepatic peroxisome proliferation in rodents (Cohen & Grasso, 1981). The structures of these two compounds and some other peroxisonie proliferators are shown in Fig. 1 . Treatment with clof...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1986
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198605000-00007