Phytochemical Screening, Antioxidant Effect and Down Regulation of TGF-β Induced by Ophiocoma erinaceus Brittle Star Crude Extract
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چکیده
منابع مشابه
Anti-inflammatory properties of saponin fraction from (Spiny brittle star) Ophiocoma erinaceus (Müller and Troschel, 1842)
Marine saponins are naturally glycosides compounds which possess important biomedical properties such as anti-cancer, antioxidant and anti-inflammatory. Nevertheless, no systematic studies on the anti-inflammatory potential of brittle star saponin and its underlying mechanisms have been reported. In this study, Ophiocoma erinaceus extracted saponin was investigated for its in vitro anti-inflamm...
متن کاملHemolytic and cytotoxic effects of saponin like compounds isolated from Persian Gulf brittle star ( Ophiocoma erinaceus )
Hemolytic and cytotoxic effects of saponin like compounds isolated from Persian Gulf brittle star (Ophiocoma erinaceus) Elaheh Amini*, Mohammad Nabiuni, Javad Baharara, Kazem Parivar, Javad Asili Developmental Biology, Kharazmi University, Tehran, Iran Biology, Research Center For Applied Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran Cell and Developmental Biology, Science and...
متن کاملMetastatic Inhibitory and Radical Scavenging Efficacies of Saponins Extracted from the Brittle Star (Ophiocoma erinaceus).
Echinodermata use saponins in chemical defense against pathogens and predators. The molecular mechanisms of antimetastatic effects of brittle star saponins are still unknown. The present study examined antioxidant capacity and invasive ability in HeLa carcinoma cells exposed to brittle star crude saponins. Discolorating methods with DPPH and ABTS and expression of SOD-2 with RT-PCR were used to...
متن کاملThe in vitro and in silico Anticholinesterase Ac-tivities of Brittle Star (Ophiocoma erinaceus) crude venoms from the Persian Gulf-Bushehr
Background: Brittle stars can produce well-known toxins responsible for various of their biological activities in addition to their physical defense. The purpose of this study was to identify secondary metabolites and assess the anticholinesterase activities of the crude venom of the Persian Gulf Ophiocoma erinaceous (brittle star) in vitro and in silico due to the abundance of this marine life...
متن کاملThe regenerative properties of the extracted polysaccharide from Brittle star (Ophiocoma erinaceus) on cutaneous wound in male Wistar rat
In traditional medicine, extracts of polysaccharide-containing plants are widely employed for the treatment of cutaneus wounds. The brittle star, as one of marine organisms, encompasses bioactive compounds, which confer the healing potency of damaged arms. The aim of the present study is to investigate the effects of extracted polysaccharide from the Persian Gulf brittle star )Ophiocoma erinace...
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ژورنال
عنوان ژورنال: Zahedan Journal of Research in Medical Sciences
سال: 2015
ISSN: 2383-2894
DOI: 10.17795/zjrms-5194