Phytochemical screening, antioxidant activity and potential toxicity of Azadirachta indica A. Juss (neem) leaves

نویسندگان

چکیده

Introduction: Azadirachta indica A. Juss, popularly known as neem, has been gaining ground in alternative herbal medicine. This plant offers a constant source of new and unique phytochemicals that are used the development drugs. Aim: A preliminary chemical analysis was carried out to detect secondary metabolites present crude hydroethanolic extract dried macerated leaves evaluate its antioxidant toxic potential. Methodology: The analysis, which performed according procedure described literature, identified data positive for phenols, tannins, leucoanthocyanidins, catechins, flavones, flavonoids xanthones, absence anthocyanins, anthocyanidins, chalcones, aurones, flavonols flavanones. Results: quantitative test by DPPH method, an ultraviolet-visible spectrophotometer, revealed moderate at highest concentration 250.0 μg.mL-1. An investigation toxicity potential against larvae Artemia salina Leach, indicated LC50 = 596.7 μg.mL-1, placing it within range when compared literature. Conclusion: These studies therefore indicate contains substances with medicinal properties is safe therapeutic purposes.

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Neem, neem tree, Indian lilac, margosa, nimtree [English]; margousier, margosier, neem [French]; nim, margosa, lila india [Spanish]; amargosa [Portuguese]; Niembaum [German]; mimba [Indonesian]; mwarobaini [Kiswahili]; sầu đâu [Vietnamese]; عئاش مين [Arabic]; [Bengali]; [Burmese]; [Gujarati]; תידוה תכרדזא [Hebrew]; [Hindi]; インドセンダン [Japanese]; [Kannada]; [Marathi]; [Mayalayam]; [Nepalese]; [Pen...

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ژورنال

عنوان ژورنال: Revista Colombiana de Ciencias Químico - Farmacéuticas

سال: 2021

ISSN: ['0034-7418', '1909-6356']

DOI: https://doi.org/10.15446/rcciquifa.v50n1.95447