Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts

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Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts

The antioxidant potentials of a total ethanolic extract of Hypericum perforatum (TE) and fractions were evaluated and correlated with their phenolic contents. The extracts were fully characterised by HPLC–DAD–MS–MS. Kaempferol 3-rutinoside and rutinacetyl were identified for the first time in TE extracts. The free radical-scavenging properties of TE (EC50 1⁄4 21 lg dwb/ml) and fractions were st...

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Comparative phytochemical and antimicrobial investigations of Hypericum perforatum L. subsp. perforatum and H. perforatum subsp. angustifolium (DC.) Gaudin.

The aerial parts of H. perforatum subsp. perforatum and H. perforatum subsp. angustifolium were investigated for their chemical composition and antimicrobial activity. Spectrophotometric analysis indicated that H. perforatum subsp. perforatum is richer in flavonoids and tannins than the other subspecies. HPLC analysis confirmed the higher yield of flavonoids in H. perforatum subsp. perforatum a...

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Antioxidant activity relationship of phenolic compounds in Hypericum perforatum L.

BACKGROUND The St John's Wort (Hypericum perforatum; Clusiaceae) has been used in traditional and modern medicine for a long time due to its high content of biologically active phenolics. The purpose of this work was to develop a method for their fractionation and identification, and to determine the most active antioxidant compounds in plant extract. RESULTS An LC-MS method which enables fas...

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Transgenic Hypericum perforatum.

Plant transformation is an important tool with many applications in modern plant biology. Although this technique is primarily used to produce superior crop varieties, it is also being utilized to answer basic questions concerning gene function and regulation in contemporary functional genomics research. In our laboratory, we have established a transformation system for Hypericum perforatum. Th...

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Hypericum perforatum: nature's mood stabilizer.

Hypericum perforatum (HP), better known as St. John's Wort, has been used clinically for centuries. Modern usage is still quite diverse and includes kidney and lung ailments, insomnia and depression. Standardised extracts of HP are widely used in the treatment of psychovegetative disorders and especially for mild forms of depression. Several bioactive constituents of this plant may play importa...

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ژورنال

عنوان ژورنال: Food Chemistry

سال: 2005

ISSN: 0308-8146

DOI: 10.1016/j.foodchem.2004.03.049