Phytochemical analysis and anticancer activity of Majidea zanguebarica Kirk Ex Oliv

Phytochemicals are secondary metabolites that naturally produced by plants. The main aim of the study is to investigate presence phyto constituents in flowers Majidea zanguebarica through GC-MS analysis. Phytochemical screening was carried out using methanol, benzene, petroleum ether and chloroform extracts which revealed alkaloids, flavonoids, steroids, tannins, saponins, fatty acids, carbohydrates cardio glycosides. analysis methanolic flower extract evidenced 28 compounds M. zanguebarica. highest amount carbohydrate amino acid content were present 0.175 mg/g 0.269 respectively. In vitro antioxidant activity such as DPPH radical scavenging activity, hydroxyl total reducing power analyzed. Radical found be higher flowers. MTT assay, IC50 value for 25 µg/ml concentration. DNA fragmentation study, maximum fragments observed high concentration extract. It concluded has tendency activate cell death process treated cells. This investigation might further evaluated its anticancer potential a significant level.