Physostigmine use in clozapine intoxication from adulterated heroin: an atypical toxidrome with an effective antidote
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چکیده
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Physostigmine as an Antidote
Introduction: Rapid treatment of patients with anticholinergic toxicity in the Ernergcncy Department (ED) has remained problematic for many years. These patients are often agitated. uncooperative, and unable to provide a clear history. Physostigmine is a specific antidote for anticholinergic toxicity. yet its popularity has waned due to controversy surrounding its potential central nervo~is sys...
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15 صفحه اولAtypical Neuroleptic Malignant Syndrome Associated with Use of Clozapine
The Neuroleptic Malignant Syndrome (NMS) is a medical emergency of infrequent presentation in the emergency department, which is associated with the use of psychiatric drugs, such as typical and atypical antipsychotics. Our case addresses a 55-year-old patient diagnosed with undifferentiated schizophrenia for 10 years, who had been receiving clozapine and clonazepam as part of their treatment. ...
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Topical application of eye drops may cause mild or severe adverse ocular or systemic effects. Children, particularly infants, are more prone to systemic adverse effects of topical eye drops because of their lower body mass and blood volume, immature metabolism, and immaturity of excretory, nervous, and cardiovascular systems. Early recognition of signs and symptoms of systemic toxicity is very ...
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ژورنال
عنوان ژورنال: Toxicology Communications
سال: 2018
ISSN: 2473-4306
DOI: 10.1080/24734306.2018.1472870