Physiology of Basal Ganglia Disorders: An Overview
نویسندگان
چکیده
منابع مشابه
Physiology of basal ganglia disorders: an overview.
The pathophysiology of the movement disorders arising from basal ganglia disorders has been uncertain, in part because of a lack of a good theory of how the basal ganglia contribute to normal voluntary movement. An hypothesis for basal ganglia function is proposed here based on recent advances in anatomy and physiology. Briefly, the model proposes that the purpose of the basal ganglia circuits ...
متن کاملTHE CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES Physiology of the Basal Ganglia: An Overview
The major anatomical connections of the basal ganglia are reviewed, emphasizing the inputs to the striatum and efferent projections from the major output nuclei, the internal segment of globus pallidus and the pars reticulata of substantia nigra. The results from lesioning experiments, electrical stimulation, and chronic recording of single neuron activity have provided a wealth of data concern...
متن کاملThe Behavioural Neurology of Basal Ganglia Disorders
Basal ganglia disorders are common clinical conditions characterised by specific motor dysfunction and associated behavioral problems. The underlying pathophysiology primarily consists in alterations of the cortico-striato-thalamo-cortical pathways, which can be related to both neurodegenerative pathology (e.g. Parkinson disease, Huntington disease) and neurodevelopmental processes (e.g. Touret...
متن کاملThe functional anatomy of basal ganglia disorders.
Basal ganglia disorders are a heterogeneous group of clinical syndromes with a common anatomic locus within the basal ganglia. To account for the variety of clinical manifestations associated with insults to various parts of the basal ganglia we propose a model in which specific types of basal ganglia disorders are associated with changes in the function of subpopulations of striatal projection...
متن کاملBrain Stimulation for Basal Ganglia Disorders
The basal ganglia (BG) have long been considered a purely motor region of the brain. However, over the last couple of decades it has progressively become clear that BG are central components of different cortical-subcortical circuits, described on a basic level as ‘motor’, ‘oculomotor’, ‘associative’ and ‘limbic’, according to the function of the cortical regions involved [1]. In turn, each cir...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1993
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100047909