Physiologic regulation of arterial pressure. An overview.

Regulation of Arterial Pressure

Three anephric patients were studied during sequential periods of normal hydration and overhydration. The increase in arterial pressure caused by the overhydration (+ 7% of body weight) was associated with an increase in peripheral resistance (+ 21.1%, P < 0.01). The elevation of peripheral resistance was preceded by an increased cardiac output (+ 22.3%, P < 0.02) which then fell part way to co...

Vasopressin and Arterial Pressure Regulation

Data from conscious rats, dogs, and humans show that plasma arginine vasopressin (AVP) begins to exert vasoconstrictor activity at concentrations in the same range as those associated with maximum antidiuretic activity. Minimum pressor responses are observed with elevated plasma AVP, due in part to decreases of cardiac output and in part to withdrawal of sympathetic neural tone to various regio...

Splenorenal reflex regulation of arterial pressure.

During the course of our studies into the control of fluid extravasation from the splenic vasculature, we found that intrasplenic inhibition of NO biosynthesis caused an increase in systemic blood pressure. The present experiments were designed to investigate the mechanisms underlying this novel observation. There was an increase in mean arterial pressure when the nonspecific NO inhibitor N(G)-...

Central regulation of arterial blood pressure.

Pulmonary Arterial Hypertension: An Overview

Pulmonary hypertension (PH) is a hemodynamic state defined by a resting mean pulmonary artery pressure (PAP) at or above 25 mm Hg.[1] with normal left ventricular filling pressure (mean pulmonary wedge pressure) 15 mmHg or less. Pre-capillary PH is defined as mean PAP ≥25 mm Hg in association with PAOP ≤15 mm Hg and a pulmonary vascular resistance (PVR) >3 Wood units. This include group 1, 3, 4...