منابع مشابه
Physico-chemical foundations underpinning microarray and next-generation sequencing experiments
Hybridization of nucleic acids on solid surfaces is a key process involved in high-throughput technologies such as microarrays and, in some cases, next-generation sequencing (NGS). A physical understanding of the hybridization process helps to determine the accuracy of these technologies. The goal of a widespread research program is to develop reliable transformations between the raw signals re...
متن کاملPhysico-Chemical Disintegration of Concrete
The purpose of this paper is to list and discuss briefly some of the causes of chemical and physico-chemical disintegration of concrete and to point out some methods that can be used to study these causes. In this paper a distinction is made between physico-chemical (or chemico-physical) and mechanical causes of failure. Processes involving changes in chemical composition (chemical reactions pr...
متن کاملIncorporation of Physico-chemical Parameters into Design of Oligo Probes for Microarray Experiments
Background: Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes. It is frequently assumed that eliminating self-complementarity, or screening for secondary structure in the probe, is sufficient to avoid interference with hybridization by stable secondary structures in the probe binding site. Predicti...
متن کاملSURVEY AND SUMMARY Physico-chemical foundations underpinning microarray and next-generation sequencing experiments
Hybridization of nucleic acids on solid surfaces is a key process involved in high-throughput technologies such as microarrays and, in some cases, nextgeneration sequencing (NGS). A physical understanding of the hybridization process helps to determine the accuracy of these technologies. The goal of a widespread research program is to develop reliable transformations between the raw signals rep...
متن کاملPhysico-chemical Processes for Landfill Leachate Treatment: Experiments and Mathematical Models
In this study, the adsorption of synthetic landfill leachate onto four kinds of activated carbon has been investigated. From the equilibrium and kinetics experiments, it was observed that coal based PAC presented the highest organic pollutants removal efficiency (54%), followed by coal based GAC (50%), wood based GAC (33%) and wood based PAC (14%). The adsorption equilibrium of PAC and GAC was ...
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ژورنال
عنوان ژورنال: Nature
سال: 1882
ISSN: 0028-0836,1476-4687
DOI: 10.1038/026126e0