Physical Characteristic of the Aorta in Young Stroke-Prone Hypertensive Rat
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چکیده
منابع مشابه
Hypertensive changes in intratesticular arteries impair spermatogenesis of the stroke-prone spontaneously hypertensive rat.
It is reported that some elderly males exhibit both hypospermatogenesis and intratesticular arterial changes. These arterial changes are thought to contribute to spermatogenic damage. In this study the process of the damage to spermatogenesis induced by such changes was evaluated using stroke-prone spontaneously hypertensive rats (SHRSP). SHRSP showed a rapid increase of blood pressure, followe...
متن کاملStroke-Prone Spontaneously Hypertensive Rats
Background and Purpose We examined metabolic and functional changes when forebrain ischemia was induced in strokeprone spontaneously hypertensive rats by bilateral carotid artery occlusion. In addition, the protective effect of clentiazem was evaluated in this model. Methods Rats were anesthetized with urethane. Cerebral blood flow was measured with a laser Doppler fkrwmeter. Cerebral high-ener...
متن کاملImpaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat.
BACKGROUND AND PURPOSE To identify if the stroke-prone spontaneously hypertensive rat (SHRSP) exhibits impaired functional recovery after stroke compared with its normotensive reference strain, the Wistar Kyoto rat (WKY). METHODS In study 1, a 2-mm distal middle cerebral artery occlusion (middle cerebral artery occlusion) was performed in both strains and recovery assessed using a 33-point ne...
متن کاملPhysical characteristics of the aortas in old stroke-prone spontaneously hypertensive rats.
In order to study the possible alteration of arterial walls in relation to the genetic desposition of stroke, the physical characteristics of the aortas in stroke-prone SHR (SHRSP) and Kyo: Wister (WK), which was the origin of SHR, were investigated previously and was reported that the aorta of SHRSP was more brittle than those of WK (Jap Heart J 16: 293, 1975). We modified the technique to det...
متن کاملCharacterization of the microglial response to cerebral ischemia in the stroke-prone spontaneously hypertensive rat.
Stroke-prone spontaneously hypertensive rats (SHRSP) sustain more ischemic damage after middle cerebral artery occlusion than do their reference strain, the Wistar-Kyoto rat (WKY). The cause of increased stroke sensitivity is still under investigation. In general, SHRSP display a greater response to inflammatory stimuli than do WKY. Because inflammatory cells may influence the extent of damage ...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1977
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.18.588