Phthalocyanine iron nanodots for combined chemodynamic-sonodynamic cancer therapy

Recent advances of sonodynamic therapy in cancer treatment

Sonodynamic therapy (SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer which offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. In this ar...

Optical Studies in Magnesium Phthalocyanine, Iron Phthalocyanine and Zinc Phthalocyanine Thin Films

Spectral studies of metal phthalocyanines are invaluable in the understanding of the electronic processes in phthalocyanines. The electronic overlap between the centrally substituted metal ion and the phthalocyanine ring can be observed from charge transfer (CT) transition between the central metal ion and the phthalocyanine ligand and point to extensive coupling between the two electronic syst...

Iron therapy and cancer.

Anemia in cancer patients has many etiologies. Iron therapy clearly is indicated in patients whose anemias are associated with iron deficiency. However, a frequent cause of anemia in cancer is the "anemia of chronic disorders," in which, although functional iron may be low, tissue iron remains normal or high. Administration of iron with erythropoietin to such patients requires careful and frequ...

Case report: A breast cancer patient treated with GcMAF, sonodynamic therapy and hormone therapy.

BACKGROUND Gc protein-derived macrophage-activating factor (GcMAF) occurs naturally in the human body. It has various functions, such as macrophage activation and antitumor activities. Recently, immunotherapy has become an attractive new strategy in the treatment of cancer. GcMAF-based immunotherapy can be combined with many other therapies. Sonodynamic therapy (SDT) using low-intensity ultraso...

Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo.