منابع مشابه
Video-rate functional photoacoustic microscopy at depths.
We report the development of functional photoacoustic microscopy capable of video-rate high-resolution in vivo imaging in deep tissue. A lightweight photoacoustic probe is made of a single-element broadband ultrasound transducer, a compact photoacoustic beam combiner, and a bright-field light delivery system. Focused broadband ultrasound detection provides a 44-μm lateral resolution and a 28-μm...
متن کاملSuper-resolution photoacoustic microscopy using photonic nanojets: a simulation study.
Optical resolution photoacoustic microscopy (ORPAM) is important for various biomedical applications, such as the study of cellular structures, microcirculation systems, and tumor angiogenesis. However, the lateral resolution of a conventional ORPAM is limited by optical diffraction. In this work, we report a simulation study to achieve subdiffraction-limited super-resolution in ORPAM using mic...
متن کاملPhotoacoustic Microscopy.
Photoacoustic microscopy (PAM) is a hybrid in vivo imaging technique that acoustically detects optical contrast via the photoacoustic effect. Unlike pure optical microscopic techniques, PAM takes advantage of the weak acoustic scattering in tissue and thus breaks through the optical diffusion limit (~1 mm in soft tissue). With its excellent scalability, PAM can provide high-resolution images at...
متن کاملSuper-resolution microscopy at a glance.
Advances in microscopy and cell biology are intimately intertwined, with new visualization possibilities often leading to dramatic leaps in our understanding of how cells function. The recent unprecedented technical innovation of super-resolution microscopy has changed the limits of optical resolution from ~250 nm to ~10 nm. Biologists are no longer limited to inferring molecular interactions f...
متن کاملGrueneisen relaxation photoacoustic microscopy.
The temperature-dependent property of the Grueneisen parameter has been employed in photoacoustic imaging mainly to measure tissue temperature. Here we explore this property using a different approach and develop Grueneisen relaxation photoacoustic microscopy (GR-PAM), a technique that images nonradiative absorption with confocal optical resolution. GR-PAM sequentially delivers two identical la...
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ژورنال
عنوان ژورنال: SPIE Newsroom
سال: 2008
ISSN: 1818-2259
DOI: 10.1117/2.1200809.1277