Phosphorylation of Dynamin I on Ser-795 by Protein Kinase C Blocks Its Association with Phospholipids
نویسندگان
چکیده
منابع مشابه
Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals.
The septins are a family of GTPase enzymes required for cytokinesis and play a role in exocytosis. Among the ten vertebrate septins, Sept5 (CDCrel-1) and Sept3 (G-septin) are primarily concentrated in the brain, wherein Sept3 is a substrate for PKG-I (cGMP-dependent protein kinase-I) in nerve terminals. There are two motifs for potential PKG-I phosphorylation in Sept3, Thr-55 and Ser-91, but ph...
متن کاملPhosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription.
Nrf2, a basic leucine zipper transcription factor, is an essential activator of the coordinated transcription of genes encoding antioxidant enzymes and phase II detoxifying enzymes through the regulatory sequence termed antioxidant response element (ARE). Recently we reported evidence for the involvement of protein kinase C (PKC) in phosphorylating Nrf2 and triggering its nuclear translocation ...
متن کاملPhosphorylation of Human CTP Synthetase 1 by Protein Kinase C IDENTIFICATION OF Ser AND Thr AS MAJOR SITES OF PHOSPHORYLATION*
Phosphorylation of human CTP synthetase 1 by mammalian protein kinase C was examined. Using purified Escherichia coliexpressed CTP synthetase 1 as a substrate, protein kinase C activity was timeand dose-dependent and dependent on the concentrations of ATP and CTP synthetase 1. The protein kinase C phosphorylation of the recombinant enzyme was accompanied by a 95-fold increase in CTP synthetase ...
متن کاملRegulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase.
The expression of c-myc promotes cell proliferation and also sensitizes cells to various extracellular apoptotic stimuli. However, signal pathways regulating the function of Myc proteins during apoptosis are unknown. c-Jun N-terminal kinase (JNK) is activated by various apoptotic stimuli, but neither the target molecule(s) or the action of JNK has been identified in Myc-mediated apoptosis. Here...
متن کاملImpact of site-specific phosphorylation of protein kinase A sites Ser and Ser of cardiac troponin I in human cardiomyocytes
Paul J. M. Wijnker, D. Brian Foster, Allison L. Tsao, Aisha H. Frazier, Cristobal G. dos Remedios, Anne M. Murphy, Ger J. M. Stienen, and Jolanda van der Velden Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands; Division of Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryla...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2000
ISSN: 0021-9258
DOI: 10.1074/jbc.275.16.11610