Phospholamban expressed in slow-twitch and chronically stimulated fast-twitch muscles minimally affects calcium affinity of sarcoplasmic reticulum Ca(2+)-ATPase.
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چکیده
منابع مشابه
Properties of the fragmented sarcoplasmic reticulum from fast twitch and slow twitch muscles.
Skeletal muscle of guinea pigs is composed of at least three types of fibers which are distinguishable by their kinetic and histochemical properties. Fast twitch muscles may be histochemically red or white; fragmented sarcoplasmic reticulum (FSR) prepared from both types of fast twitch muscles has identical calcium-accumulating capacity (maximal calcium uptake) and calcium-concentrating ability...
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The 31-amino acid proteolipid, sarcolipin (SLN), is associated with the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase (SERCA1). Constructs of human and rabbit SLN and of rabbit SLN with the FLAG epitope at its N terminus (NF-SLN) or its C terminus (SLN-FC) were coexpressed with SERCA1 in HEK-293 T-cells. Immunohistochemistry was used to demonstrate colocalization of NF-SLN and ...
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The rabbit cardiac/slow twitch muscle sarcoplasmic reticulum (SR) Ca2+ ATPase (SERCA2) gene encodes a Ca2+ transport pump whose expression is regulated during skeletal/cardiac muscle development and by different pathophysiological states of the heart. This study was designed to delineate cis-acting regulatory elements involved in SERCA2 gene expression. A series of unidirectionally deleted frag...
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The purpose of this study was to determine whether methyl jasmonate, a stimulator of Ca(2+)-adenosine triphosphatase (ATPase) activity of the purified ATPase from fast-twitch skeletal muscle, could affect contractile responses in small bundles of rat isolated slow-twitch (soleus) fibers. In saponin-skinned fibers, sarcoplasmic reticulum (SR) Ca(2+) loading was performed in pCa 7.0 solution. The...
متن کاملMethyl Jasmonate-Induced Stimulation of Sarcoplasmic Reticulum Ca -ATPase Affects Contractile Responses in Rat Slow-Twitch Skeletal Muscle
The purpose of this study was to determine whether methyl jasmonate, a stimulator of Ca -adenosine triphosphatase (ATPase) activity of the purified ATPase from fast-twitch skeletal muscle, could affect contractile responses in small bundles of rat isolated slow-twitch (soleus) fibers. In saponin-skinned fibers, sarcoplasmic reticulum (SR) Ca loading was performed in pCa 7.0 solution. The amount...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)35716-8