Phosphatidylethanol (PEth); the Superior Direct Alcohol Biomarker against Mean Corpuscular Volume (MCV), Aspartate Amino Transferase (AST), Alanine Aminotransferase (ALT), Gamma-Glutamyl Transferase (GGT) and Carbohydrate-Deficient Transferrin (CDT)
نویسندگان
چکیده
منابع مشابه
Common reference intervals for aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT) in serum: results from an IFCC multicenter study.
BACKGROUND Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT) measurements are important for the assessment of liver damage. The aim of this study was to define the reference intervals (RIs) for these enzymes in adults, paying attention to standardization of the methods used and careful selection of the reference population. METHODS AST, ALT and ...
متن کاملPhosphatidylethanol Compared with Other Blood Tests as a Biomarker of Moderate Alcohol Consumption in Healthy Volunteers: A Prospective Randomized Study.
AIM It is generally agreed that traditional alcohol biomarkers lack in sensitivity to detect hazardous alcohol consumption. The present study was undertaken to evaluate the ability of phosphatidylethanol (PEth) and traditional alcohol markers to detect moderate alcohol consumption and to distinguish between moderate alcohol consumption and abstinence. METHODS Forty-four subjects, 32 females a...
متن کاملBlood biomarkers of alcohol abuse.
The biological, clinical and social effects of alcohol abuse call for objective and specific biomarkers of alcohol-related diseases and early detection of alcohol consumers at risk. Alcohol abusers may exhibit several clinical and/or chemical changes. Changes in parameters such as gamma-glutamyltransferase (GGT), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and mean corpusc...
متن کاملComparison of the combined marker GGT-CDT and the conventional laboratory markers of alcohol abuse in heavy drinkers, moderate drinkers and abstainers.
AIMS A combined index based on gamma-glutamyltransferase (GGT) and carbohydrate-deficient transferrin (CDT) measurements (GGT-CDT) has been recently suggested to improve the detection of excessive ethanol consumption. The aim of this work was to compare GGT-CDT with the conventional markers of alcohol abuse in individuals with a wide variety of alcohol consumption. METHODS A cross-sectional a...
متن کاملObjective Diagnosis of Chronic Alcohol Abuse - Determination of Carbohydrate-Deficient Transferrin (CDT) with Capillary Electrophoresis.
To assist the diagnosis of high risk alcohol consumption or alcohol dependence, particularly in the absence of evidences of recent alcohol intake (relapse), objective biochemical markers are today available, which, if used correctly, may reduce the degree of subjectivity that the adoption of merely clinical and psychological diagnostic criteria shows inevitably. The present paper reviews briefl...
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ژورنال
عنوان ژورنال: American Journal of Biomedical Science & Research
سال: 2019
ISSN: 2642-1747
DOI: 10.34297/ajbsr.2019.03.000623