Phosphate-independent calcium efflux from liver mitochondria
نویسندگان
چکیده
منابع مشابه
The action of Nupercaine on calcium efflux from rat liver mitochondria.
1. Nupercaine inhibits the Ca2+ efflux from rat liver mitochondria observed in the presence of Ruthenium Red, 50% inhibition being obtained at 80 microM-Nupercaine. 2. Neither the Ruthenium Red-stimulated efflux nor its inhibition by Nupercaine can be directly attributed to effects on mitochondrial stability. 3. Nupercaine perturbs the steady-state external Ca2+ concentration in the absence of ...
متن کاملEfflux of adenine nucleotides from rat liver mitochondria.
A rapid and selective efflux of 75 to 80% of the intramitochondrial adenine nucleotides (AdN) has been obtained by incubation with 5 mm Mgff and 10 mM inorganic phosphate in the presence of 1 mM ethylenediaminetetraacetate, with little or no decrease in the P:O ratio, active respiratory state, or size of the pyridine nucleotide pool. The initial rate of AdN efflux is 5 nmoles per mg of protein ...
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The et&x of aspartate from rat heart and liver mitochondria is facilitated by energy derived from the electron transport chain or from adenosine triphosphate. The metabolic significance of this finding resides in the fact that aspartate efflux from mitochondria is required for operation of the malate-aspartate cycle, which is a major pathway for the energy-requiring transport of reducing equiva...
متن کاملEfflux of Adenine Nucleotides from Rat Liver Mitochondria*
A rapid and selective efflux of 75 to 80% of the intramitochondrial adenine nucleotides (AdN) has been obtained by incubation with 5 mm Mgff and 10 mM inorganic phosphate in the presence of 1 mM ethylenediaminetetraacetate, with little or no decrease in the P:O ratio, active respiratory state, or size of the pyridine nucleotide pool. The initial rate of AdN efflux is 5 nmoles per mg of protein ...
متن کاملPhosphate transport in rat-liver mitochondria.
Vesicles have been prepared by mild sonication of a purified inner membrane fraction from rat liver mitochondria. Such vesicles demonstrate an energy-dependent net concentrative uptake of inorganic phosphate in the absence of added Na+, Ca’+, or ionophores. Phosphate uptake can be supported by a variety of substrates including /?-hydroxybutyrate, succinate, and ascorbate + tetramethylphenylened...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1981
ISSN: 0014-5793
DOI: 10.1016/0014-5793(81)80097-x