منابع مشابه
Charcoal hemoperfusion for phenytoin intoxication.
Accidental ingestion of phenytoin can lead to severe neurological sequelae. Charcoal hemoperfusion decreases phenytoin levels but has never been reported before in children. We present a child with accidental ingestion of phenytoin who responded to charcoal hemoperfusion.
متن کاملPhenytoin intoxication during treatment with parenteral miconazole.
We describe a patient in whom phenytoin toxicity developed soon after treatment with parenteral miconazole. A 51 year old man was admitted for treatment of recurrent severe haemoptysis associated with pulmonary aspergillosis. He was in chronic respiratory failure. He was a non-smoker. Biochemical 'indices of liver function were normal. There was a past history of asthma and also of epilepsy for...
متن کاملPhenytoin intoxication during concurrent diazepam therapy.
Phenytoin elimination is a saturable process obeying Michaelis-Menten kinetics. Plasma phenytoin levels are not related linearly to dose, and small changes in enzyme activity produced by concurrent drug therapy could alter plasma levels. Two cases of phenytoin intoxication associated with simultaneous administration of diazepam are reported. Intravenous phenytoin infusions were given and the ap...
متن کاملPhenytoin Intoxication: Burden and risk factors.
OBJECTIVE The aim of the study is to determine: 1) the frequency of patients admitted for phenytoin toxicity and their economic burden; 2) the clinical symptoms and signs of intoxication; 3) the causes or risk factors of intoxication, and 4) the ways to prevent phenytoin toxicity. METHODS Retrospective review of hospital ICD coded database between 1987 and 1998. All patients with phenytoin in...
متن کاملSevere intoxication after phenytoin infusion: a preventable pharmacogenetic adverse reaction.
Neurology G. Citerio, A. Nobili, L. Airoldi, R. Pastorelli and A. Patruno adverse reaction Severe intoxication after phenytoin infusion: A preventable pharmacogenetic This information is current as of November 24, 2009 http://www.neurology.org/cgi/content/full/60/8/1395 located on the World Wide Web at: The online version of this article, along with updated information and services, is All righ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1970
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5687.48