Phenytoin Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)

Phenytoin-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: A case report.

BACKGROUND Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an uncommon but serious hypersensitivity drug reaction most frequently associated with antiepileptics. Clinical manifestations include rash, fever, and visceral organ involvement, most commonly hepatitis. The mortality rate associated with DRESS syndrome is approximately 10%, the majority due to fulminant liver fai...

DRESS Syndrome: Drug Reaction With Eosinophilia and Systemic Symptoms.

DRESS syndrome is a cutaneous and systemic drug reaction with severe complications and a long course that can be fatal. Recognition may be difficult, and the condition is just rare enough that clinicians will eventually see it but may not be familiar with it. This review will focus on key elements to help clinicians with the challenges of recognition and differential diagnosis.

Bosentan-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome.

Severe ceftazidime-induced drug reaction with eosinophilia and systemic symptoms (DRESS)

In vitro tests Fourteen months after the drug reaction, in vitro tests to identify the causal agent were performed. The lymphocyte transformation test (LTT) showed a marked proliferation to ceftazidime (stimulation index (SI): 17 at 100mcg/mL). CD25 was upregulated on CD4+ (induced expression: 17%) and CD8+ (induced expression: 8%) T cells as shown by flow cytometry when cultured with ceftazidi...

Sulthiame-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome.

BACKGROUND Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially life-threatening acute drug-induced hypersensitivity reaction. Antiepileptic drugs (AEDs) predominantly aromatic AEDs are commonly reported in DRESS. To date there are no reports of sulthiame AED causing DRESS syndrome. METHOD We report a 10-year-old girl of Indian descent with AED resi...