Phenytoin-induced acute orofacial dyskinesia

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Teaching Video NeuroImages: phenytoin-induced orofacial dyskinesias.

Brendan P. Lucey, MD A 55-year-old right-handed man started phenytoin after 2 seizures. Four weeks later, he complained of involuntary facial movements. Examination revealed orofacial dyskinesias: eyebrow elevation and lip pursing (video on the Neurology Web site at www. neurology.org). No ataxia, slurred speech, or nystagmus was seen. His phenytoin level was 29.5 mg/L when examined, increased ...

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Objective(s):Long-term treatment with antipsychotics causes serious side effects such as tardive dyskinesia that characterized by abnormal movements in the orofacial region. Oxidative stress in the brain specific area is implicated in the pathophysiology of tardive dyskinesia. In this study the protective effect of crocin on haloperidol-induced orofacial dyskinesia was evaluated. Materials and ...

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crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism

objective(s):long-term treatment with antipsychotics causes serious side effects such as tardive dyskinesia that characterized by abnormal movements in the orofacial region. oxidative stress in the brain specific area is implicated in the pathophysiology of tardive dyskinesia. in this study the protective effect of crocin on haloperidol-induced orofacial dyskinesia was evaluated. materials and ...

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ژورنال

عنوان ژورنال: Neurología (English Edition)

سال: 2013

ISSN: 2173-5808

DOI: 10.1016/j.nrleng.2012.02.005