Phenytoin, folic acid and gingival enlargement: Breaking myths
نویسندگان
چکیده
منابع مشابه
Phenytoin-induced gingival enlargement.
To cite: Chacko LN, Abraham S. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014204670 DESCRIPTION Gingival overgrowth occurs as a side effect of some systemic medications. It is now well established that phenytoin is one such agent. It has multiple therapeutic indications ranging from convulsive disorders and neuralgias to cardiac arrhythmia. The incidence rat...
متن کاملPeriodontal Management of Phenytoin Induced Gingival Enlargement: A Case Report
Gingival enlargement or gingival overgrowth is the abnormal growth of periodontal tissues. Drug induced gingival enlargement is one of the most common cause of enlarged gingiva. Drugs associated with gingival enlargement are divided in to three major groups namely anticonvulsants, immunosuppressant and calcium channel blockers [1]. Among the anticonvulsants, phenytoin is most commonly associate...
متن کاملManagement of phenytoin-induced gingival enlargement: a case report.
Gingival enlargements may adversely affect speech, mastication, tooth eruption, and esthetics. These enlargements can occur as a result of the administration of certain anticonvulsants, immunosuppressants, and calcium channel blockers. The present case report describes the treatment of a patient with a phenytoin-induced gingival enlargement. A case of gingival enlargement should be treated in a...
متن کاملStimulation and inhibition of fibroblast subpopulations by phenytoin and phenytoin metabolites: pathogenetic role in gingival enlargement
Functional heterogeneity exists among fibroblasts in gingiva. There is remarkable variation in the protein synthetic activities, the proliferative capacities and the drug-response potentials of various subpopulations of such cells. These functional differences may play a role in the pathogenesis of phenytoin-induced gingival enlargement, as subpopulation mixtures are altered by conditions withi...
متن کاملPhenytoin-induced gingival overgrowth.
Gingival overgrowth is a common adverse effect of therapy with Phenytoin, having important medical and cosmetic implications. Poor periodontal hygiene is an important risk factor for severity of Phenytoin-induced gingival overgrowth (PIGO), which is a time-dependent process. There is complex interplay of altered fibroblast biology, connective tissue turnover, inflammatory processes, and growth ...
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ژورنال
عنوان ژورنال: Contemporary Clinical Dentistry
سال: 2014
ISSN: 0976-237X
DOI: 10.4103/0976-237x.128666