Phenotypic transitions enacted by simulated microgravity do not alter coherence in gene transcription profile
نویسندگان
چکیده
منابع مشابه
Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells
Microgravity exerts dramatic effects on cell morphology and functions, by disrupting cytoskeleton and adhesion structures, as well as by interfering with biochemical pathways and gene expression. Impairment of cells behavior has both practical and theoretical significance, given that investigations of mechanisms involved in microgravity-mediated effects may shed light on how biophysical constra...
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During spaceflight the normal head-to-foot hydrostatic pressure gradients are eliminated and body fluids shift toward the head, resulting in a diminished fluid volume in the legs and an increased fluid volume in the head, neck, and upper extremities. Lymphatic function is important in the maintenance of normal tissue fluid volume, but it is not clear how microgravity influences lymphatic pumpin...
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ژورنال
عنوان ژورنال: npj Microgravity
سال: 2019
ISSN: 2373-8065
DOI: 10.1038/s41526-019-0088-x