Phenotypic detection and incidence of inducible clindamycin resistance among Staphylococcus aureus from tertiary care hospital

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Inducible clindamycin resistance among Staphylococcus aureus isolates

Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...

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Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital.

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Incidence of constitutive and inducible clindamycin resistance among hospital-associated Staphylococcus aureus

Clindamycin is one of the important alternative antibiotics in the therapy of Staphylococcus aureus infections. Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolides, lincosamides and Streptogramin B (MLSB) antibiotics. In vitro routine tests for clindamycin susceptibility may fail to detect inducible clindamycin resistance due...

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detection of inducible clindamycin resistance (mlsbi) among methicillin-resistant staphylococcus aureus (mrsa) isolated from health care providers

methicillin-resistant staphylococcus aureus (mrsa) is one of the most important agents producing nosocomial diseases in hospitalized children. then, screening of health care providers who are in direct contact with patients in hospital is necessary. the objective of this study was to investigate mrsa collected isolates for mlsb phenotypes, in particular inducible clindamycin resistance (mlsbi)....

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Inducible clindamycin resistance due to expression of erm genes in Staphylococcus aureus: report from a tertiary care Hospital Karachi, Pakistan.

OBJECTIVE To assess the frequency of phenotypic expression of inducible resistance of clindamycin due to expression of erm genes, in clinical isolates of Staphylococcus aureus (S. aureus), by double disk diffusion test (D-test). METHOD This was a cross sectional study conducted in the clinical laboratory of Aga Khan University Hospital, Karachi. A total of 2432, non duplicate clinical isolate...

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ژورنال

عنوان ژورنال: International Journal of Advances in Medicine

سال: 2015

ISSN: 2349-3925

DOI: 10.18203/2349-3933.ijam20150557