Phenolic profiling by UPLC–MS/MS and hepatoprotective activity of Cardiospermum halicacabum against CCl4 induced liver injury in Wistar rats
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EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF GLYCOSMIS PENTAPHYLLA ROOTS AGAINST CCl4 – INDUCED ACUTE LIVER INJURY IN RATS
Glycosmis pentaphylla (Rutaceae) are well known in India as Ashvashakota, Vananimbuka, Pathalagarudi (Sanskrit), Ban-nimbu (Hindi), Kirmira (Marathi) Golugu and Gongipadu (Telugu) of ethyl acetate and methanolic extracts (100, 200 and 400 mg/kg) was prepared and tested for its hepatoprotective effect against carbon tetrachloride induced in rats. Alteration in the levels of biochemical markers o...
متن کاملHepatoprotective Activity of Caspian Saffron (Crocus caspius Fisch and Mey) Flowers against CCl4- Induced Acute Liver Injury in Mice
Background and objectives: Free radicals and other oxidants have important roles in liver cell toxicity. Some natural products are potent scavengers of oxidative agents. Crocus caspius is an endemic species of Caspian forest. Flowers of Crocus genus contain phenolic compound and carotenoid as antioxidant agent. This study investigated the antioxidant and hepat...
متن کاملHepatoprotective Activity of Cucumis trigonus Roxb. Fruit Against CCl4 Induced Hepatic Damage in Rats
In India, a number of medicinal plants and their formulations are used to cure hepatic disorders in traditional systems of medicine. No systemic study has been done on protective effect of Cucumis trigonus Roxb. (Cucurbitaceae) to treat hepatic diseases. Protective action of C. trigonus fruit extracts was evaluated in this study in animal model of hepatotoxicity, which was induced by carbon tet...
متن کاملHepatoprotective Activity of Cucumis trigonus Roxb. Fruit Against CCl4 Induced Hepatic Damage in Rats
In India, a number of medicinal plants and their formulations are used to cure hepatic disorders in traditional systems of medicine. No systemic study has been done on protective effect of Cucumis trigonus Roxb. (Cucurbitaceae) to treat hepatic diseases. Protective action of C. trigonus fruit extracts was evaluated in this study in animal model of hepatotoxicity, which was induced by carbon tet...
متن کاملHepatoprotective activity of aerial parts of Otostegia persica against carbon tetrachloride-induced liver damage in rats
Objective: To evaluate the hepatoprotective properties of Otostegia persica (O. persica) ethanol extract on carbon tetrachloride-induced liver damage in rats. Materials and Methods: Fifty adult male Wistar rats were randomly divided into five groups. Group I served as normal control and was given only olive oil intraperitoneally (i.p.). Group II, III, IV, and V were administered CCl4 mixed wi...
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ژورنال
عنوان ژورنال: Journal of Functional Foods
سال: 2013
ISSN: 1756-4646
DOI: 10.1016/j.jff.2012.10.019