منابع مشابه
Detection of drugs of abuse in nails.
Postmortem toenail samples were used for the detection of cocaine (COC), benzoylecgonine (BZE), norcocaine (NCOC), cocaethylene (CE), morphine (MOR), 6-monoacetylmorphine (6-MAM), codeine (COD), and hydrocodone (HDC). After the toenail clippings were washed with methanol, they were solubilized in 0.1 M potassium phosphate (pH 5.0). The drugs of interest, along with internal standards, were isol...
متن کاملDetection and quantitation of phencyclidine in blood by use of [(2)H(5)] phencyclidine and select ion monitoring applied to non-fatal cases of phencyclidine intoxication.
Phencyclidine [PCP, Sernyl#{174}, 1-(1-phencyclohexyl) piperidine] is a potent analgesic originally developed as an intravenous anesthetic. Deemed unsuitable for human use, it is currently marketed legitimately as a primate tranquilizer. The illegitimate use of phencyclidine has increased drastically throughout the United States since its “discovery” on the West Coast by the so-called drug cult...
متن کاملHalf and half nails (Lindsay's nails) in chronic renal disease.
A 19 year old male, student, presented with a history of progressive loss of vision from right eye since one and half year and from the left eye since one year. The patient also complained of multiple episodes of generalized seizures three months back. Patient was diagnosed with tubercular choroiditis with chronic kidney disease with seizure disorder. The patient was evaluated but no intracrani...
متن کاملAnti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats.
These studies examined the hypothesis that a single large dose of monoclonal anti-phencyclidine (PCP) antibody could provide long-term reductions in brain PCP concentrations despite continuous PCP administration. PCP (18 mg/kg/day, s.c.) was infused to steady-state (24 h) and then a mole-equivalent dose of a short-acting anti-PCP antigen-binding fragment (Fab) or a long-acting anti-PCP IgG was ...
متن کاملCerebellar toxicity of phencyclidine.
Phencyclidine (PCP), dizocilpine maleate (MK801), and other NMDA antagonists are toxic to neurons in the posterior cingulate and retrosplenial cortex. To determine if additional neurons are damaged, the distribution of microglial activation and 70 kDa heat shock protein (HSP70) induction was studied following the administration of PCP and MK801 to rats. PCP (10-50 mg/kg) induced microglial acti...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2006
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/30.8.643