Phase-Variance Optical Coherence Tomography

3 Phase - Resolved Doppler Optical Coherence Tomography

Transverse Priority Phase Sensitive Optical Coherence Tomography

A variation on the standard time domain optical coherence tomography (TDOCT) system is presented. Using an inexpensive piezoelectric stack to modulate the reference mirror position, the amplitude and phase of the sample reflection is determined without scanning. With the primary scan in the transverse direction, en face and B-scan OCT images can be readily produced with phase information. This ...

Retinal angiography with real-time speckle variance optical coherence tomography.

This report describes a novel, non-invasive and label-free optical imaging technique, speckle variance optical coherence tomography (svOCT), for visualising blood flow within human retinal capillary networks. This imaging system uses a custom-built swept source OCT system operating at a line rate of 100 kHz. Real-time processing and visualisation is implemented on a consumer grade graphics proc...

Speckle variance optical coherence tomography for imaging microcirculation

Non-invasive flow detection and in-vivo measurement are one of the most requested clinical applications for medical imaging modalities to investigate vascular pathologies and responsiveness to drug therapy. Implementing speckle variance calculation & visualization in a market-proven optical coherence tomography (OCT) system we demonstrate an angiography imaging algorithm that provides angle ind...

Complex differential variance algorithm for optical coherence tomography angiography.

We describe a complex differential variance (CDV) algorithm for optical coherence tomography based angiography. The algorithm exploits both the intensity and phase changes of optical coherence tomography (OCT) signals from flowing blood to achieve high vascular contrast, and also intrinsically reject undesirable phase signals originating from small displacement axial bulk tissue motion and inst...