Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy

XWH - 04 - 1 - 0262 TITLE : Targeting MRS - Defined Dominant Intraprostatic Lesions with Inverse - Planned High Dose Rate Brachytherapy

Dose escalation using conformal high-dose-rate brachytherapy improves outcome in unfavorable prostate cancer.

PURPOSE To overcome radioresistance for patients with unfavorable prostate cancer, a prospective trial of pelvic external beam irradiation (EBRT) interdigitated with dose-escalating conformal high-dose-rate (HDR) prostate brachytherapy was performed. METHODS AND MATERIALS Between November 1991 and August 2000, 207 patients were treated with 46 Gy pelvic EBRT and increasing HDR brachytherapy b...

Applicator Attenuation Effect on Dose Calculations of Esophageal High-Dose Rate Brachytherapy Using EDR2 Film

Introduction Interaluminal brachytherapy is one of the important methods of esophageal cancer treatment. The effect of applicator attenuation is not considered in dose calculation method released by AAPM-TG43. In this study, the effect of High-Dose Rate (HDR) brachytherapy esophageal applicator on dose distribution was surveyed in HDR brachytherapy. Materials and Methods A cylindrical PMMA phan...

High-Dose-Rate 192Ir Brachytherapy Dose Verification: A Phantom Study

BACKGROUND The high-dose-rate (HDR) brachytherapy might be an effective tool for palliation of dysphagia. Because of some concerns about adverse effects due to absorbed radiation dose, it is important to estimate absorbed dose in risky organs during this treatment. OBJECTIVES This study aimed to measure the absorbed dose in the parotid, thyroid, and submandibular gland, eye, trachea, spinal c...

Fractionated High-Dose-Rate Brachytherapy

Purpose: A growing body of data suggests that local control in nasopharyngeal cancer (NPC) is related to the radiation dose administered. We conducted a singleinstitution study of high-dose radiotherapy (RT), which incorporated high-dose-rate (HDR) brachytherapy (BT). These results were analyzed together with data obtained from controls who did not receive BT. Patients and Methods: The BT group...