منابع مشابه
Pharmacovigilance of Oncology Biosimilars
Biologicals are critical in cancer medicine. Four of the top ten biological blockbusters worldwide are oncology drugs used for therapeutic or supportive care. The global market for biologic cancer therapies approximately totalled US$ 51.2 billion in 2014 and is expected to reach US$ 66.4 billion in 2019. The patents of most of these top-selling agents will expire by the year 2020 attracting ind...
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The introduction in clinical practice of pharmaceutical products known as biosimilars, as part of a more complex series of progress in the field of biological drugs, represents an excellent therapeutic resource. A biosimilar drug is a biological/biotechnological drug that is highly similar to an approved reference biologic product. Given their complexity, biosimilars require attention and a con...
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When new anticancer medications are approved, their safety profiles are often not fully understood. Oncology nurses have a responsibility to file reports of adverse drug events with safety registries such as MedWatch. If these registries receive prompt, complete, and accurate data from clinicians, agencies such as the U.S. Food and Drug Administration will have a stronger ability to detect haza...
متن کاملRelevance of the Weber effect in contemporary pharmacovigilance of oncology drugs
BACKGROUND Numerous reporting biases have been known to affect spontaneous reporting databases. The Weber effect, which constitutes a peak in adverse event (AE) reporting of a drug at the end of second year after regulatory approval followed by a continuous decline thereafter, has been considered an important bias for a long time. The existence of this bias in AE reporting of oncology drugs rem...
متن کاملBrain mapping in Neurosurgical oncology
After the introduction of MRI, new modalities facilitated the procedure of surgical planning to achieve the microsurgical goal and improve prognosis and quality of life in patients. Despite the variable applications of preoperative and intraoperative mapping and monitoring systems, several limitations and concerns are reported for every modality as well. In this issue of the IrJNS, we are delig...
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ژورنال
عنوان ژورنال: International Journal of Clinical Pharmacy
سال: 2018
ISSN: 2210-7703,2210-7711
DOI: 10.1007/s11096-018-0706-9